Detalhe da pesquisa
1.
An apical membrane complex for triggering rhoptry exocytosis and invasion in Toxoplasma.
EMBO J
; 41(22): e111158, 2022 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36245278
2.
Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite.
J Lipid Res
; 59(8): 1461-1471, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29853527
3.
High Accumulation and In Vivo Recycling of the New Antimalarial Albitiazolium Lead to Rapid Parasite Death.
Antimicrob Agents Chemother
; 61(8)2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607017
4.
Uncovering new structural insights for antimalarial activity from cost-effective aculeatin-like derivatives.
Org Biomol Chem
; 13(7): 2064-77, 2015 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25519040
5.
New insight into the mechanism of accumulation and intraerythrocytic compartmentation of albitiazolium, a new type of antimalarial.
Antimicrob Agents Chemother
; 58(9): 5519-27, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25001307
6.
Design, synthesis and evaluation of new tricyclic endoperoxides as potential antiplasmodial agents.
Org Biomol Chem
; 12(28): 5212-21, 2014 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24914508
7.
Flexible synthesis and evaluation of diverse anti-Apicomplexa cyclic peptides.
J Org Chem
; 78(8): 3655-75, 2013 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23535138
8.
Forming spirocyclohexadienone-oxocarbenium cation species in the biomimetic synthesis of amomols.
J Org Chem
; 76(5): 1409-17, 2011 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21250723
9.
An Alveolata secretory machinery adapted to parasite host cell invasion.
Nat Microbiol
; 6(4): 425-434, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33495622
10.
Rodent and nonrodent malaria parasites differ in their phospholipid metabolic pathways.
J Lipid Res
; 51(1): 81-96, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19561325
11.
Reliability of antimalarial sensitivity tests depends on drug mechanisms of action.
J Clin Microbiol
; 48(5): 1651-60, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20220159
12.
Reverse-benzamidine antimalarial agents: design, synthesis, and biological evaluation.
Bioorg Med Chem Lett
; 20(19): 5815-7, 2010 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20800484
13.
Exploration of potential prodrug approach of the bis-thiazolium salts T3 and T4 for orally delivered antimalarials.
Bioorg Med Chem Lett
; 20(13): 3953-6, 2010 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20605450
14.
A lipid-binding protein mediates rhoptry discharge and invasion in Plasmodium falciparum and Toxoplasma gondii parasites.
Nat Commun
; 10(1): 4041, 2019 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31492901
15.
G-Quadruplex Identification in the Genome of Protozoan Parasites Points to Naphthalene Diimide Ligands as New Antiparasitic Agents.
J Med Chem
; 61(3): 1231-1240, 2018 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29323491
16.
Hydroxyl Ketone-Based Histone Deacetylase Inhibitors To Gain Insight into Class I HDAC Selectivity versus That of HDAC6.
ACS Omega
; 2(4): 1550-1562, 2017 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30023639
17.
Synthesis of an Uncharged Tetra-cyclopeptide Acting as a Transmembrane Carrier: Enhanced Cellular and Nuclear Uptake.
Org Lett
; 19(3): 612-615, 2017 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28107021
18.
Mono- and bis-thiazolium salts have potent antimalarial activity.
J Med Chem
; 48(10): 3639-43, 2005 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-15887971
19.
Development of the first oral bioprecursors of bis-alkylguanidine antimalarial drugs.
ChemMedChem
; 9(2): 300-4, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24403182
20.
Disulfide prodrugs of albitiazolium (T3/SAR97276): synthesis and biological activities.
J Med Chem
; 55(10): 4619-28, 2012 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22591034